Publication:
Modified method for determination of hippuric acid and methylhippuric acid in urine by gas chromatography

Issued Date

2001-02-10

Resource Type

Article

ISSN

13872273

DOI

10.1016/S0378-4347(00)00463-1

Other identifier(s)

2-s2.0-0035835411

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Chromatography B: Biomedical Sciences and Applications. Vol.751, No.1 (2001), 199-203

Suggested Citation

P. Kongtip, J. Vararussami, V. Pruktharathikul Modified method for determination of hippuric acid and methylhippuric acid in urine by gas chromatography. Journal of Chromatography B: Biomedical Sciences and Applications. Vol.751, No.1 (2001), 199-203. doi:10.1016/S0378-4347(00)00463-1 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/26517

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Title

Modified method for determination of hippuric acid and methylhippuric acid in urine by gas chromatography

Author(s)

P. Kongtip
 J. Vararussami
 V. Pruktharathikul

Other Contributor(s)

Mahidol University
 Air Quality and Noise Management Bureau

Abstract

A modified method for the simultaneous determination of hippuric acid (HA) and o-, m- and p-methylhippuric acids (o-, m- and p-MHAs) in urine is described. These metabolites were extracted, derivatized into their methyl ester derivatives and analyzed using a gas chromatograph equipped with flame ionization detector and a DB-1 capillary column. The derivatives of HA, o-, m- and p-MHAs were well separated within 11 min. The accuracy and precision in the present method were sufficient for quantitative analysis, and the results obtained by the GC method were highly correlated with those by the HPLC method (NIOSH 8301). © 2001 Elsevier Science B.V.

Keyword(s)

Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/26517

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Scopus 2001-2005