Publication:
Downregulation of plasma miR-451 and miR-16 in Plasmodium vivax infection

dc.contributor.authorSupat Chamnanchanunten_US
dc.contributor.authorChieri Kurokien_US
dc.contributor.authorVarunee Desakornen_US
dc.contributor.authorMari Enomotoen_US
dc.contributor.authorVipa Thanachartweten_US
dc.contributor.authorDuangjai Sahassanandaen_US
dc.contributor.authorJetsumon Sattabongkoten_US
dc.contributor.authorRachaneeporn Jenwithisuken_US
dc.contributor.authorSuthat Fucharoenen_US
dc.contributor.authorSaovaros Svastien_US
dc.contributor.authorTsukuru Umemuraen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherInternational University of Health and Welfareen_US
dc.date.accessioned2018-11-23T10:16:21Z
dc.date.available2018-11-23T10:16:21Z
dc.date.issued2015-08-01en_US
dc.description.abstract© 2015 . Malaria is a common parasitic disease in tropical countries, causing one to two million deaths every year. To establish the new biomarker, we analyzed plasma miRNAs obtained from 19 malaria patients and 19 normal subjects, using reverse transcription-based quantitative polymerase chain reaction (RT-qPCR). The average levels of plasma miR-451 and miR-16 were significantly lower in malaria patients, (8.9-fold; p <. 0.001 and 10.4-fold; p = 0.01, respectively). The levels of other abundant miRNAs in plasma (miR-223, miR-226-3p) did not change significantly in malaria patients. Our data suggest that plasma miR-451 and miR-16 are relevant biomarkers for malaria infection.en_US
dc.identifier.citationExperimental Parasitology. Vol.155, (2015), 19-25en_US
dc.identifier.doi10.1016/j.exppara.2015.04.013en_US
dc.identifier.issn10902449en_US
dc.identifier.issn00144894en_US
dc.identifier.other2-s2.0-84929377420en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/36089
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84929377420&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.titleDownregulation of plasma miR-451 and miR-16 in Plasmodium vivax infectionen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84929377420&origin=inwarden_US

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