Publication: Comparative studies of two oral contraceptives containing DL norgestrel and D norgestrel
Issued Date
1973-12-01
Resource Type
ISSN
01252208
Other identifier(s)
2-s2.0-0015788411
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.56, No.5 (1973), 314-318
Suggested Citation
S. Koetsawang, S. Rimdusit, S. Srivanaboon, P. Bhiraleus, D. Rachawat Comparative studies of two oral contraceptives containing DL norgestrel and D norgestrel. Journal of the Medical Association of Thailand. Vol.56, No.5 (1973), 314-318. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10154
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Title
Comparative studies of two oral contraceptives containing DL norgestrel and D norgestrel
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Abstract
Preliminary REPORTS on the comparative studies of 2 combined oral contraceptives: dl norgestrel 0.5 mg + ethinyl estradiol 0.05 mg (compound 1) and d norgestrel 0.25 mg + ethinyl estradiol 0.05 (compound 2) in 200 sexually active women are presented. The study showed that the effects of both compounds on menstruation and the side effects of both drugs were almost identical. Because of the relatively low incidence of side effects, both combinations were well accepted and well tolerated by the women. Concerning the long term effects of the drugs, a previous study with compound 1 showed that the drug was safe in the women for at least a period of 5 yr. Compound 2, which is biologically as active as compound 1 but has a smaller dose of progestogen should be preferable owing to metabolic reasons. This study also shows that the pack of 28 tablets is easier to prescribe in busy clinics as less time is needed in explaining the method of pill taking.