Publication: A negative anion gap as a clue to diagnose bromide intoxication
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Issued Date
1995-01-01
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ISSN
00282766
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2-s2.0-0028963959
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Mahidol University
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SCOPUS
Bibliographic Citation
Nephron. Vol.69, No.3 (1995), 311-313
Suggested Citation
S. Vasuvattakul, N. Lertpattanasuwan, K. Vareesangthip, S. Nimmannit, S. Nilwarangkur A negative anion gap as a clue to diagnose bromide intoxication. Nephron. Vol.69, No.3 (1995), 311-313. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/17449
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Title
A negative anion gap as a clue to diagnose bromide intoxication
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Abstract
We report on a patient with bromide intoxication, presenting with confusion, disorientation, and auditory and visual hallucinations after taking a sedative medication containing bromide (mixture menopause; 15 ml containing 1 g potassium bromide) for I month. Blood chemistry showed a high chloride level (176 mEq/l) and a negative anion gap (-60 mEq/l). The spurious hyperchloremia was due to interference of chloride ion determination by the ion-selective electrode method with a high level of bromide in serum. 352 mg/dl (44 mEq/l). In this case the only striking abnormality which alerted the physician to the possibility of halide intoxication was the negative anion gap. Hence, a negative anion gap is an important clue which leads to the diagnosis of halide intoxication.