Publication: Electrospinning: A carbonized gold/graphene/PAN nanofiber for high performance biosensing
Issued Date
2018-02-28
Resource Type
ISSN
17599679
17599660
17599660
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2-s2.0-85042584526
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Mahidol University
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SCOPUS
Bibliographic Citation
Analytical Methods. Vol.10, No.8 (2018), 874-883
Suggested Citation
Pongpol Ekabutr, Wimonwan Klinkajon, Pakakrong Sangsanoh, Orawan Chailapakul, Pimolpan Niamlang, Thitikan Khampieng, Pitt Supaphol Electrospinning: A carbonized gold/graphene/PAN nanofiber for high performance biosensing. Analytical Methods. Vol.10, No.8 (2018), 874-883. doi:10.1039/c7ay02880f Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/45435
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Title
Electrospinning: A carbonized gold/graphene/PAN nanofiber for high performance biosensing
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Abstract
© 2018 The Royal Society of Chemistry. In this study, a novel biosensor was produced from a carbonized gold (Au)/graphene (G) hybrid nanowire fabricated on a disposable screen-printed carbon electrode (SPCE) in order to amplify signals. The processes of carbonization and electrospinning were merged in order to determine dopamine (DA) in a selective and sensitive manner when it is present in uric acid (UA) or ascorbic acid (AA). In order to assess the nature of the surface morphology and the physical product properties, transmission electron microscopy, scanning electron microscopy, and X-ray diffraction were employed prior to and following the carbonization step. The modified electrode (CPAN-Au/G) in [Fe(CN)6]3-/4- and DA was examined using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) in order to establish the electrochemical behavior. The findings from this test revealed that the modified electrode was capable of selectively identifying DA in 0.1 M PBS at pH 7.4 when other substances were present to provide interference. This process did not require the use of an anionic surfactant to serve as the discriminating agent. From the analysis of the DPV current, a linear dependence upon DA concentrations became apparent, in the range of 0.001-60 μM when the detection limit was 0.8 nM (S/N = 3) and sensitivity was 1.4351 μA cm-2. DA quantities in human serum could be effectively detected using the CPAN-Au/G electrode, and the modified electrode raises considerable expectations for application as a high-potential electrode. This would permit the determination of DA in a selective and sensitive manner while achieving sensor stability over the long term.
