Publication:
Dynamic voltage threshold adjusted substrate modification technique for complex atypical atrial flutters with varying circuits

dc.contributor.authorNilubon Methachittiphanen_US
dc.contributor.authorNazem Akoumen_US
dc.contributor.authorRakesh Gopinathnairen_US
dc.contributor.authorPatrick Boyleen_US
dc.contributor.authorArun R. Sridharen_US
dc.contributor.otherFaculty of Medicine, Ramathibodi Hospital, Mahidol Universityen_US
dc.contributor.otherUniversity of Washington, Seattleen_US
dc.contributor.otherKansas City Heart Rhythm Institute and Research Foundationen_US
dc.date.accessioned2020-10-05T06:53:35Z
dc.date.available2020-10-05T06:53:35Z
dc.date.issued2020-01-01en_US
dc.description.abstract© 2020 Wiley Periodicals LLC Background: Atypical atrial flutter (AFL) is common in patients with postsurgical atrial scar, with macro- or microscopic channels in the scar acting as substrate for reentry. Heterogeneous atrial scarring can cause varying flutter circuits, which makes mapping and ablation challenging, and recurrences common. Aim: We hypothesize that dynamically adjusting voltage thresholds can identify heterogeneous atrial scarring, which can then be effectively homogenized to eliminate atypical AFLs. Methods: We studied consecutive patients who presented to Electrophysiology laboratory for atypical AFL ablation with history of atriotomy and included the patients with multiple, varying flutter circuits during mapping in our study. We excluded patients with stable flutter circuit that was sustained and could be localized using traditional entrainment and activation mapping strategy. In the included patients, we performed detailed high-density voltage map of the atrium of interest. We adjusted voltage thresholds as needed to identify heterogeneity and channels in the scarred regions. A thorough scar homogenization was performed with irrigated smart-touch ablation catheter. Re-inducibility of tachycardia, and immediate and long-term outcomes were studied. Results: Of five studied cases, one was female; age 66 ± 10 years. All five had prior surgical substrate. All the patients had multiple flutter morphologies, which varied as we mapped the AFL. After scar homogenization, tachycardia was not inducible in any patient. No recurrence of flutter was noted during a mean follow-up duration of 450 ± 27 days. Conclusion: High-density voltage mapping and homogenization of the scar can be an effective strategy in eliminating complex scar-mediated atypical AFL with multiple circuits.en_US
dc.identifier.citationPACE - Pacing and Clinical Electrophysiology. (2020)en_US
dc.identifier.doi10.1111/pace.14068en_US
dc.identifier.issn15408159en_US
dc.identifier.issn01478389en_US
dc.identifier.other2-s2.0-85091438700en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/59295
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85091438700&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleDynamic voltage threshold adjusted substrate modification technique for complex atypical atrial flutters with varying circuitsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85091438700&origin=inwarden_US

Files

Collections