Publication: HLA Class II Allele Frequencies in Northern Thais (Kamphaeng Phet)
Issued Date
1997-01-01
Resource Type
ISSN
01252208
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2-s2.0-0042048516
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.80, No.SUPPL. 1 (1997)
Suggested Citation
Ratchaneewan Maneemaroj, Henry A.F. Stephens, Dasnayanee Chandanayingyong, Komon Longta, Sasitorn Bejrachandra HLA Class II Allele Frequencies in Northern Thais (Kamphaeng Phet). Journal of the Medical Association of Thailand. Vol.80, No.SUPPL. 1 (1997). Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/18205
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Title
HLA Class II Allele Frequencies in Northern Thais (Kamphaeng Phet)
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Abstract
The polymorphism of HLA class II genes (HLA-DRB1, -DQA1, -DQB1 and -DPB1) was investigated in 97 normal Northern Thais (NT) from Kamphaeng Phet province using PCR-SSO typing. Allele frequencies (AF) have been determined. DRB1*1202 (17.5%), DRB1*1502 (16.5%), DQA1*0101 (25.8%), DQA1*0102 (21.7%), DQB1*0502 (22.7%), DPB1*0501 (23.2%) and DPB 1*1301 (22.7%) showed the highest frequencies in each locus. These results were more similar to those observed in Present-day Thais (PDT) and Central Thais (CT) than Northern Thais from Chiang Mai (CM) and Dai Lue (DL). However, the data presented in this population study should be useful in many fields, such as anthropology, organ transplantation, disease susceptibility and evolutionary genetics.