Publication: Classification of the parenchymal cells in Fasciola gigantica based on ultrastructure and their expression of fatty acid binding proteins (FABPs)
Issued Date
2006-12-20
Resource Type
ISSN
03044017
Other identifier(s)
2-s2.0-33751008402
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Veterinary Parasitology. Vol.142, No.3-4 (2006), 281-292
Suggested Citation
Viriya Pankao, Anuchittada Sirisriro, Rudi Grams, Suksiri Vichasri-Grams, Ardool Meepool, Niwat Kangwanrangsan, Chaitip Wanichanon, Pissanee Ardseungneon, Vithoon Viyanant, Edward Suchart Upatham, Prasert Sobhon Classification of the parenchymal cells in Fasciola gigantica based on ultrastructure and their expression of fatty acid binding proteins (FABPs). Veterinary Parasitology. Vol.142, No.3-4 (2006), 281-292. doi:10.1016/j.vetpar.2006.07.009 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/22850
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Classification of the parenchymal cells in Fasciola gigantica based on ultrastructure and their expression of fatty acid binding proteins (FABPs)
Other Contributor(s)
Abstract
Parenchymal cells in adult Fasciola gigantica can be classified into three types based on their ultrastructural features and different quantities of fatty acid binding protein (FABP) being stored. Parenchymal cell type 1 (Pc1) has pale cytoplasm consisting largely of a loose network of fine fibers, and it contains few mitochondria but numerous glycogen particles. This cell type may be specialized in the storage and metabolism of glycogen and glucose. Parenchymal cell type 2 (Pc2) has similar cytoplasmic features as Pc1but contains more numerous mitochondria, and high concentration of FABP as reflected by high density of immunostaining and immunogold labeling using specific monoclonal antibody (MoAb) to FABP as probe. Pc2may, thus, specialize in the storage and metabolism of fatty acids and other lipids. Parenchymal cell type 3 (Pc3) has dense cytoplasm containing large amount of rough endoplasmic reticulum, Golgi complex and mitochondria, which is typical of a secretory cell. Furthermore, Pc3has very little glycogen particles and is not stained by MoAb against FABP. It could, thus, be concerned with the synthesis of fibers, which form the scaffold of the parenchyma. © 2006 Elsevier B.V. All rights reserved.