Publication:
Early posttransplant nephrotic range proteinuria as a presenting feature of minimal change disease and acute T cell-mediated rejection

Issued Date

2014-01-01

Resource Type

Article

ISSN

18732623
00411345

DOI

10.1016/j.transproceed.2012.07.140

Other identifier(s)

2-s2.0-84893759255

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Transplantation Proceedings. Vol.46, No.1 (2014), 290-294

Suggested Citation

A. Nongnuch, M. Assanatham, V. Sumethkul, P. Chalermsanyakorn, C. Kitiyakara Early posttransplant nephrotic range proteinuria as a presenting feature of minimal change disease and acute T cell-mediated rejection. Transplantation Proceedings. Vol.46, No.1 (2014), 290-294. doi:10.1016/j.transproceed.2012.07.140 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34477

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Early posttransplant nephrotic range proteinuria as a presenting feature of minimal change disease and acute T cell-mediated rejection

Author(s)

A. Nongnuch
 M. Assanatham
 V. Sumethkul
 P. Chalermsanyakorn
 C. Kitiyakara

Other Contributor(s)

Mahidol University

Abstract

Early-onset nephrotic range proteinuria is an extremely rare presentation of an acute rejection episode. Herein, we have reported a patient who developed nephrotic range proteinuria 7 days after receiving a renal allograft from his sister despite minor changes in serum creatinine levels. A kidney biopsy spcimen revealed a T cell-mediated acute rejection process concomitant with minimal change disease (MCD). Proteinuria and renal dysfunction improved dramatically in response to corticosteroids. The possibility of acute cellular rejection and coexisting MCD should be considered in patients with early posttransplantation nephrosis and normal serum creatinine levels. The coexistence of these entities provides support for the role of T cells in the pathogenesis of MCD. © 2012 Elsevier Inc. © 2014 by Elsevier Inc. All rights reserved.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/34477

Collections

Scopus 2011-2015