Publication: Management of Severe Insulin Resistance in Patients with Type 1 Diabetes
Issued Date
2015-10-22
Resource Type
ISSN
15390829
15344827
15344827
Other identifier(s)
2-s2.0-84939633568
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Current Diabetes Reports. Vol.15, No.10 (2015)
Suggested Citation
Sirimon Reutrakul Management of Severe Insulin Resistance in Patients with Type 1 Diabetes. Current Diabetes Reports. Vol.15, No.10 (2015). doi:10.1007/s11892-015-0641-2 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/36285
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Management of Severe Insulin Resistance in Patients with Type 1 Diabetes
Author(s)
Other Contributor(s)
Abstract
© 2015, Springer Science+Business Media New York. Managing severe insulin resistance (IR) in patients with type 1 diabetes (T1DM) can be challenging for both clinicians and patients. As average weight for patients with T1DM has increased in recent decades, IR in this population has become more widespread. Currently, almost 50 % of patients with T1DM are overweight or obese. While intensive insulin therapy is associated with reduction in complications, aggressive treatment can lead to weight gain. With increasing weight, insulin can become less effective to control glycemia, resulting in higher insulin doses and hence more weight gain. Novel strategies to break this vicious cycle are needed. This review will investigate current research on insulin formulations, lifestyle modification, adjunct therapies, and surgery that may help better manage patients with T1DM and IR.