Publication: Genotypic study of Pneumocystis jirovecii in human immunodeficiency virus-positive patients in Thailand
Issued Date
2005-05-01
Resource Type
ISSN
00951137
Other identifier(s)
2-s2.0-18644365229
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Clinical Microbiology. Vol.43, No.5 (2005), 2104-2110
Suggested Citation
Suradej Siripattanapipong, Jeerapun Worapong, Mathirut Mungthin, Saovanee Leelayoova, Peerapan Tan-Ariya Genotypic study of Pneumocystis jirovecii in human immunodeficiency virus-positive patients in Thailand. Journal of Clinical Microbiology. Vol.43, No.5 (2005), 2104-2110. doi:10.1128/JCM.43.5.2104-2110.2005 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/16592
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Genotypic study of Pneumocystis jirovecii in human immunodeficiency virus-positive patients in Thailand
Abstract
Pneumocystis jirovecii is one of the common opportunistic infections in human immunodeficiency virus (HIV)-infected patients in Thailand. Information regarding genotypic and epidemiological of this organism in Thai patients is not available. We analyzed the genotypes of 28 P. jirovecii-positive specimens from bronchoalveolar lavage and sputum samples from HIV-infected Thai patients based on nucleotide variations of the internal transcribed spacer regions 1 and 2 of the rRNA gene. Thirteen genotypes were the same as previously reported outside Thailand. Ten genotypes, which included Bp, Er, Eq, Ic, Ir, Ip, Rc, Rp, Qb, and Qq, were new. Ir and Rp were unique and dominant types observed in HIV-infected Thai patients. Thirteen specimens (46.4%) were infected with a single type of P. jirovecii, and fifteen (53.6%) were mixed infections. These differences may be used as genotypic markers for studying the epidemiology and transmission of P. jirovecii in the Thai population. Copyright © 2005, American Society for Microbiology. All Rights Reserved.