Publication: Acute Effect of Ethanol on Intestinal Calcium Transport
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Issued Date
1986-01-01
Resource Type
ISSN
18817742
03014800
03014800
Other identifier(s)
2-s2.0-0022697854
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Nutritional Science and Vitaminology. Vol.32, No.2 (1986), 229-236
Suggested Citation
Nateetip Krishnamra, Pornpimol Boonpimol Acute Effect of Ethanol on Intestinal Calcium Transport. Journal of Nutritional Science and Vitaminology. Vol.32, No.2 (1986), 229-236. doi:10.3177/jnsv.32.229 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/9822
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Title
Acute Effect of Ethanol on Intestinal Calcium Transport
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Abstract
In vivo studies in rats demonstrated that acute intragastric administration of ethanol (3g/kg BW) resulted in a reduced net absorption of fluid and calcium. Thirty minutes after an i.v. injection of 2μCi 45 Ca, the gastrointestinal 45 Ca content in ethanol-treated rats was significantly higher than in controls indicating an increase in calcium secretion. The effect of ethanol on calcium movement was quantitated by measuring calcium fluxes across the in situ duodenal and ileal loops. Ethanol administration suppressed net duodenal calcium absorption by inhibiting the lumen to plasma flux of calcium. In contrast, ethanol enhanced plasma to lumen calcium flux in the ileum, resulting in net calcium secretion. © 1986, Center for Academic Publications Japan. All rights reserved.