Publication: Rhodamine-based fluorescent and colorimetric sensor for zinc and its application in bioimaging
Issued Date
2016-06-02
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ISSN
09254005
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2-s2.0-84955278800
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Mahidol University
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SCOPUS
Bibliographic Citation
Sensors and Actuators, B: Chemical. Vol.228, (2016), 270-277
Suggested Citation
Kanokorn Wechakorn, Kanoknetr Suksen, Pawinee Piyachaturawat, Palangpon Kongsaeree Rhodamine-based fluorescent and colorimetric sensor for zinc and its application in bioimaging. Sensors and Actuators, B: Chemical. Vol.228, (2016), 270-277. doi:10.1016/j.snb.2016.01.045 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/40602
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Title
Rhodamine-based fluorescent and colorimetric sensor for zinc and its application in bioimaging
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Abstract
© 2016 Published by Elsevier B.V. A rhodamine derivative ZP1, appended with two 1,2,3-triazole moieties via a diaminopropyl linker, is a chromogenic and fluorogenic sensor for Zn2+. In the presence of Zn2+, a colorless solution of ZP1 becomes pink with a maximum absorption of 555 nm and a large fluorescence enhancement (140-fold) at 579 nm (Φ = 0.12). ZP1 is highly selective with Zn2+, among other metal ions including Cd2+, with a binding constant (Ka) of 7.4 × 103M-1and a detection limit of 1 μM (65 ppb). Similar rhodamine derivatives with a shorter linker or with a single triazolyl group cannot function as a Zn2+chemosensor. ZP1 is membrane-permeable and could react with intracellular Zn2+in cultured HeLa cells.