Publication: Is there any artemisinin resistance in falciparum malaria?
Issued Date
2000-12-01
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ISSN
01251562
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2-s2.0-0034577572
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.31, No.4 (2000), 825-828
Suggested Citation
Sombat Treeprasertsuk, Parnpen Viriyavejakul, Udomsak Silachamroon, Supap Vannphan, Polrat Wilairatana, Sornchai Looareesuwan Is there any artemisinin resistance in falciparum malaria?. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.31, No.4 (2000), 825-828. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/26044
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Title
Is there any artemisinin resistance in falciparum malaria?
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Abstract
We reported two cases of complicated falciparum malaria who had poor response to artesunate with delayed parasite clearance times. They were splenectomized patients who were treated with high doses of artemisinin derivatives. Our cases showed the importance of the spleen in the clearance of malaria parasites and had different clinical outcome, one fatal and one recovery. The host factors, the parasitemia count, the quality of antimalarial chemotherapy and blood level of the antimalarial drugs must be considered in relation to the causes of the delayed clearance of parasitemia.