Publication:
Changes in plasma volume and protein concentration induced by cytochalasin E in the rat: A time-course study

Issued Date

1982-01-01

Resource Type

Article

ISSN

03784274

DOI

10.1016/0378-4274(82)90045-5

Other identifier(s)

2-s2.0-0020420482

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Toxicology Letters. Vol.14, No.3-4 (1982), 157-162

Suggested Citation

Thirayudh Glinsukon, Alisa Suvannapura Changes in plasma volume and protein concentration induced by cytochalasin E in the rat: A time-course study. Toxicology Letters. Vol.14, No.3-4 (1982), 157-162. doi:10.1016/0378-4274(82)90045-5 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/30412

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Title

Changes in plasma volume and protein concentration induced by cytochalasin E in the rat: A time-course study

Author(s)

Thirayudh Glinsukon
 Alisa Suvannapura

Other Contributor(s)

Mahidol University

Abstract

Cytochalasin E produced a reduction of plasma volume and protein concentration paralleled to biphasic accumulation of peritoneal fluid at 3.0 and 6.75 h after i.p. administration to rats. At the same time, there was an accumulation of fluid in the thoracic cavity following a disappearance of peritoneal fluid in the first peak. Neither a sublethal nor a lethal dose given i.v. induced a similar response. This indicates that such changes caused by cytochalasin E given i.p. may possibly be due to adjustment of the cardiovascular system. © 1982.

Keyword(s)

Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/30412

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Scopus 1969-1990