Publication:
Bone marrow-derived mononuclear cell therapy in sepsis-induced acute respiratory distress syndrome: Different insults, different effects!

Issued Date

2013-11-26

Resource Type

Review

ISSN

17576512

DOI

10.1186/scrt354

Other identifier(s)

2-s2.0-84889002450

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Stem Cell Research and Therapy. Vol.4, No.6 (2013)

Suggested Citation

Paolo Pelosi, Yuda Sutherasan Bone marrow-derived mononuclear cell therapy in sepsis-induced acute respiratory distress syndrome: Different insults, different effects!. Stem Cell Research and Therapy. Vol.4, No.6 (2013). doi:10.1186/scrt354 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/31159

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Title

Bone marrow-derived mononuclear cell therapy in sepsis-induced acute respiratory distress syndrome: Different insults, different effects!

Author(s)

Paolo Pelosi
 Yuda Sutherasan

Other Contributor(s)

Ospedale Policlinico San Martino
 Mahidol University

Abstract

Acute respiratory distress syndrome (ARDS) is one of the devastating sequelae of sepsis, and so far no specific promising pharmacotherapies have been proven to decrease mortality from it. Stem cell therapy is a novel therapy that can promote earlier and more effective remodeling and repair of damaged lung tissue. Bone marrow-derived mononuclear cells are an alternative stem cell therapy that is safely and easily administered on the day of harvesting and yields benefits in acute disease processes like ARDS. In a recent issue of Stem Cell Research and Therapy, Maron-Gutierrez and colleagues demonstrated that the effects of transfused bone marrow-derived mononuclear cells on lung mechanics, inflammation and mortality might be different in different septic ARDS models due to different insults. © 2013 BioMed Central Ltd.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/31159

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