Publication:
Asymmetric synthesis of pentenomycin I, epipentenomycin I, and their analogs

Issued Date

2008-06-30

Resource Type

Article

ISSN

00404020

DOI

10.1016/j.tet.2008.04.089

Other identifier(s)

2-s2.0-44349090861

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Tetrahedron. Vol.64, No.27 (2008), 6315-6323

Suggested Citation

Manat Pohmakotr, Supakeat Kambutong, Patoomratana Tuchinda, Chutima Kuhakarn Asymmetric synthesis of pentenomycin I, epipentenomycin I, and their analogs. Tetrahedron. Vol.64, No.27 (2008), 6315-6323. doi:10.1016/j.tet.2008.04.089 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/18904

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Asymmetric synthesis of pentenomycin I, epipentenomycin I, and their analogs

Author(s)

Manat Pohmakotr
 Supakeat Kambutong
 Patoomratana Tuchinda
 Chutima Kuhakarn

Other Contributor(s)

Mahidol University

Abstract

The synthetic utility of the intramolecular acylation of α-sulfinyl carbanions as an efficient and general synthetic approach for the preparation of (-)-pentenomycin I (1) and (-)-epipentenomycin I (5) and their enantiomers (ent-1 and ent-5), starting from chiral (2S,5S,6S)-ester 6 and ent-6, respectively, has been demonstrated. Easy accesses to pentenomycin analogs have also been demonstrated through the Pummerer, Suzuki-Miyaura, and Sonogashira reactions. © 2008 Elsevier Ltd. All rights reserved.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/18904

Collections

Scopus 2006-2010