Publication: Causes of death in HIV-infected persons who have tuberculosis, Thailand
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Issued Date
2009-02-01
Resource Type
ISSN
10806059
10806040
10806040
Other identifier(s)
2-s2.0-63849235963
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Mahidol University
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SCOPUS
Bibliographic Citation
Emerging Infectious Diseases. Vol.15, No.2 (2009), 258-264
Suggested Citation
Kevin P. Cain, Thanomsak Anekthananon, Channawong Burapat, Somsak Akksilp, Wiroj Mankhatitham, Chawin Srinak, Sriprapa Nateniyom, Wanchai Sattayawuthipong, Theerawit Tasaneeyapan, Jay K. Varma Causes of death in HIV-infected persons who have tuberculosis, Thailand. Emerging Infectious Diseases. Vol.15, No.2 (2009), 258-264. doi:10.3201/eid1502.080942 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/28210
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Title
Causes of death in HIV-infected persons who have tuberculosis, Thailand
Abstract
Up to 50% of persons with HIV and a diagnosis of tuberculosis (TB) in Thailand die during TB treatment. In a prospective observational study, a team of physicians ascribed the cause of death after reviewing verbal autopsies (interviews of family members about events preceding death), laboratory data, and medical records. Of 849 HIV- infected TB patients enrolled, 142 (17%) died. The cause of death was TB for 38 (27%), including 6 with multidrug- resistant TB and 20 with disseminated TB; an HIV-associ- ated condition other than TB for 50 (35%); and a condition unrelated to TB or HIV for 22 (15%). Twenty-three patients (16%) were judged not to have had TB at all. Death from all causes except those unrelated to TB or HIV was less common in persons receiving antiretroviral therapy (ART). In addition to increasing the use of ART, death rates may be reduced through expanded use of modern TB diagnostic techniques.