Publication: Serotonin syndrome: A case report
Issued Date
2005-07-01
Resource Type
ISSN
01252208
01252208
01252208
Other identifier(s)
2-s2.0-25144456889
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.88, No.7 (2005), 993-996
Suggested Citation
Surachai Likasitwattanakul Serotonin syndrome: A case report. Journal of the Medical Association of Thailand. Vol.88, No.7 (2005), 993-996. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16937
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Title
Serotonin syndrome: A case report
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Abstract
Serotonin syndrome is a rare but potentially fatal complication of drugs that have effects on central nervous system serotonin. It is characterized by sudden onset of altered mental status, increased neuromuscular activity and autonomic instability. The author reports a child with suprasellar region tumor who presented with depression and obsessive-compulsive disorder and received a combination of sertaline (selective serotonin reuptake inhibitor) and clomipramine (tricyclic antidepressant). Symptoms of serotonin syndrome occurred within 24 hours after increasing the dose of sertaline. The patient's symptoms resolved rapidly with discontinuation of the offending drugs and supportive care.