Publication: Anti-HIV-1 constituents from leaves and twigs of Cratoxylum arborescens
| dc.contributor.author | Vichai Reutrakul | en_US |
| dc.contributor.author | Waraporn Chanakul | en_US |
| dc.contributor.author | Manat Pohmakotr | en_US |
| dc.contributor.author | Thaworn Jaipetch | en_US |
| dc.contributor.author | Chalobon Yoosook | en_US |
| dc.contributor.author | Jittra Kasisit | en_US |
| dc.contributor.author | Chanita Napaswat | en_US |
| dc.contributor.author | Thawatchai Santisuk | en_US |
| dc.contributor.author | Samran Prabpai | en_US |
| dc.contributor.author | Palangpon Kongsaeree | en_US |
| dc.contributor.author | Patoomratana Tuchinda | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Thailand Royal Forest Department | en_US |
| dc.date.accessioned | 2018-08-20T06:49:08Z | |
| dc.date.available | 2018-08-20T06:49:08Z | |
| dc.date.issued | 2006-12-01 | en_US |
| dc.description.abstract | Two new xanthones, 1,3,8-trihydroxy-2,4-dimethoxyxanthone (1) and 1,7-dihydroxy-2,8-dimethoxyxanthone (2), along with twelve known compounds 3-14 were isolated from leaves and twigs of Cratoxylum arborescens. Compound 1, euxanthone (4), betulinic acid (8), lup-20(29)-ene-3β,30-diol (9), 3β-hydroxyl-up-20(29)-en-30-oic acid (10) and 3,4-dihydroxybenzoic acid (11) displayed anti-HIV-1 activities in the syncytium assay usingΔTat/RevMC99 virus and the 1A2 cell line system (EC50values between 3.9 and 32.2 μg/mL with TI ranging from 1.5 to 11.7), while 1,3,7-trihydroxy-6-methoxy-4,5-diisoprenylxanthone (3), 4, and 8-10 inhibited HIV-1 reverse transcriptase with IC50values between 8.7 and 84.9 μg/mL. © Georg Thieme Verlag KG Stuttgart. | en_US |
| dc.identifier.citation | Planta Medica. Vol.72, No.15 (2006), 1433-1435 | en_US |
| dc.identifier.doi | 10.1055/s-2006-951725 | en_US |
| dc.identifier.issn | 00320943 | en_US |
| dc.identifier.other | 2-s2.0-33846195419 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/22938 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846195419&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Medicine | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Anti-HIV-1 constituents from leaves and twigs of Cratoxylum arborescens | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846195419&origin=inward | en_US |