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Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death

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dc.contributor.authorKannan Badri Narayananen_US
dc.contributor.authorManaf Alien_US
dc.contributor.authorBarry J. Barclayen_US
dc.contributor.authorQiang Chengen_US
dc.contributor.authorLeandro D'Abronzoen_US
dc.contributor.authorRita Dornetshuber-Fleissen_US
dc.contributor.authorParamita M. Ghoshen_US
dc.contributor.authorMichael J. Gonzalez Guzmanen_US
dc.contributor.authorTae Jin Leeen_US
dc.contributor.authorPo Sing Leungen_US
dc.contributor.authorLin Lien_US
dc.contributor.authorSuidjit Luanpitpongen_US
dc.contributor.authorEdward Ratovitskien_US
dc.contributor.authorYon Rojanasakulen_US
dc.contributor.authorMaria Fiammetta Romanoen_US
dc.contributor.authorSimona Romanoen_US
dc.contributor.authorRanjeet Kumar Sinhaen_US
dc.contributor.authorClement Yedjouen_US
dc.contributor.authorFahd Al-Mullaen_US
dc.contributor.authorRabeah Al-Temaimien_US
dc.contributor.authorAmedeo Amedeien_US
dc.contributor.authorDustin G. Brownen_US
dc.contributor.authorElizabeth P. Ryanen_US
dc.contributor.authorAnnamaria Colaccien_US
dc.contributor.authorRoslida A. Hamiden_US
dc.contributor.authorChiara Mondelloen_US
dc.contributor.authorJayadev Rajuen_US
dc.contributor.authorHosni K. Salemen_US
dc.contributor.authorJordan Woodricken_US
dc.contributor.authorIvana Scovassien_US
dc.contributor.authorNeetu Singhen_US
dc.contributor.authorMonica Vaccarien_US
dc.contributor.authorRabindra Royen_US
dc.contributor.authorStefano Forteen_US
dc.contributor.authorLorenzo Memeoen_US
dc.contributor.authorSeo Yun Kimen_US
dc.contributor.authorWilliam H. Bissonen_US
dc.contributor.authorLeroy Loween_US
dc.contributor.authorHyun Ho Parken_US
dc.contributor.otherYeungnam Universityen_US
dc.contributor.otherUniversiti Sultan Zainal Abidinen_US
dc.contributor.otherPlant Biotechnologies Incen_US
dc.contributor.otherSouthern Illinois Universityen_US
dc.contributor.otherUniversity of California, Davisen_US
dc.contributor.otherUniversitat Wienen_US
dc.contributor.otherUniversity of Puerto Ricoen_US
dc.contributor.otherChinese University of Hong Kongen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherThe Johns Hopkins School of Medicineen_US
dc.contributor.otherWest Virginia University Robert C. Byrd Health Sciences Centeren_US
dc.contributor.otherUniversita degli Studi di Napoli Federico IIen_US
dc.contributor.otherScripps Research Instituteen_US
dc.contributor.otherJackson State Universityen_US
dc.contributor.otherUniversity of Kuwaiten_US
dc.contributor.otherUniversita degli Studi di Firenzeen_US
dc.contributor.otherColorado State Universityen_US
dc.contributor.otherEnvironmental Protection and Health Prevention Agencyen_US
dc.contributor.otherUniversiti Putra Malaysiaen_US
dc.contributor.otherConsiglio Nazionale delle Ricercheen_US
dc.contributor.otherToxicology Research Divisionen_US
dc.contributor.otherCairo Universityen_US
dc.contributor.otherLombardi Comprehensive Cancer Centeren_US
dc.contributor.otherChhatrapati Shahuji Maharaj Medical Universityen_US
dc.contributor.otherMediterranean Institute of Oncologyen_US
dc.contributor.otherKorea Cancer Center Hospitalen_US
dc.contributor.otherOregon State Universityen_US
dc.contributor.otherGetting to Know Canceren_US
dc.date.accessioned2018-11-23T09:42:32Z
dc.date.available2018-11-23T09:42:32Z
dc.date.issued2015-06-01en_US
dc.description.abstract© The Author 2015. Cell death is a process of dying within biological cells that are ceasing to function. This process is essential in regulating organism development, tissue homeostasis, and to eliminate cells in the body that are irreparably damaged. In general, dysfunction in normal cellular death is tightly linked to cancer progression. Specifically, the up-regulation of prosurvival factors, including oncogenic factors and antiapoptotic signaling pathways, and the down-regulation of proapoptotic factors, including tumor suppressive factors, confers resistance to cell death in tumor cells, which supports the emergence of a fully immortalized cellular phenotype. This review considers the potential relevance of ubiquitous environmental chemical exposures that have been shown to disrupt key pathways and mechanisms associated with this sort of dysfunction. Specifically, bisphenol A, chlorothalonil, dibutyl phthalate, dichlorvos, lindane, linuron, methoxychlor and oxyfluorfen are discussed as prototypical chemical disruptors; as their effects relate to resistance to cell death, as constituents within environmental mixtures and as potential contributors to environmental carcinogenesis.en_US
dc.identifier.citationCarcinogenesis. Vol.36, (2015), S89-S110en_US
dc.identifier.doi10.1093/carcin/bgv032en_US
dc.identifier.issn14602180en_US
dc.identifier.issn01433334en_US
dc.identifier.other2-s2.0-84937698903en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/35450
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84937698903&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleDisruptive environmental chemicals and cellular mechanisms that confer resistance to cell deathen_US
dc.typeReviewen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84937698903&origin=inwarden_US
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