Publication:
Corchorusides A and B, new flavonol glycosides as α-glucosidase inhibitors from the leaves of Corchorus olitorius

Issued Date

2009-10-21

Resource Type

Article

ISSN

00404039

DOI

10.1016/j.tetlet.2009.08.014

Other identifier(s)

2-s2.0-69249223455

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Tetrahedron Letters. Vol.50, No.42 (2009), 5864-5867

Suggested Citation

Preecha Phuwapraisirisan, Thanchanok Puksasook, Udom Kokpol, Khanit Suwanborirux Corchorusides A and B, new flavonol glycosides as α-glucosidase inhibitors from the leaves of Corchorus olitorius. Tetrahedron Letters. Vol.50, No.42 (2009), 5864-5867. doi:10.1016/j.tetlet.2009.08.014 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/27131

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Corchorusides A and B, new flavonol glycosides as α-glucosidase inhibitors from the leaves of Corchorus olitorius

Author(s)

Preecha Phuwapraisirisan
 Thanchanok Puksasook
 Udom Kokpol
 Khanit Suwanborirux

Other Contributor(s)

Mahidol University
 Chulalongkorn University

Abstract

Corchorus olitorius, a highly fibrous vegetable commonly known as moroheiya, has long been recognized for its hypoglycemic activity. Bioassay-guided fractionation of the leaf extract led to the isolation of two new flavonol glycosides named corchorusides A and B, in addition to a major component, capsugenin-25,30-O-β-diglucopyranoside. Corchoruside A comprises a kaempferol moiety connected with caffeic acid, glucose, and a rare methyl glucuronate (MeGlcA). The occurrence of a caffeoyl moiety in corchoruside A enhanced significantly its inhibitory effect toward α-glucosidase compared to that in corchoruside B. © 2009 Elsevier Ltd. All rights reserved.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/27131

Collections

Scopus 2006-2010