Publication: Corchorusides A and B, new flavonol glycosides as α-glucosidase inhibitors from the leaves of Corchorus olitorius
Issued Date
2009-10-21
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ISSN
00404039
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2-s2.0-69249223455
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Mahidol University
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SCOPUS
Bibliographic Citation
Tetrahedron Letters. Vol.50, No.42 (2009), 5864-5867
Suggested Citation
Preecha Phuwapraisirisan, Thanchanok Puksasook, Udom Kokpol, Khanit Suwanborirux Corchorusides A and B, new flavonol glycosides as α-glucosidase inhibitors from the leaves of Corchorus olitorius. Tetrahedron Letters. Vol.50, No.42 (2009), 5864-5867. doi:10.1016/j.tetlet.2009.08.014 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/27131
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Title
Corchorusides A and B, new flavonol glycosides as α-glucosidase inhibitors from the leaves of Corchorus olitorius
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Abstract
Corchorus olitorius, a highly fibrous vegetable commonly known as moroheiya, has long been recognized for its hypoglycemic activity. Bioassay-guided fractionation of the leaf extract led to the isolation of two new flavonol glycosides named corchorusides A and B, in addition to a major component, capsugenin-25,30-O-β-diglucopyranoside. Corchoruside A comprises a kaempferol moiety connected with caffeic acid, glucose, and a rare methyl glucuronate (MeGlcA). The occurrence of a caffeoyl moiety in corchoruside A enhanced significantly its inhibitory effect toward α-glucosidase compared to that in corchoruside B. © 2009 Elsevier Ltd. All rights reserved.