Publication: Antiviral therapeutic potential of curcumin: An update
Issued Date
2021-11-01
Resource Type
ISSN
14203049
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2-s2.0-85121045210
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Mahidol University
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SCOPUS
Bibliographic Citation
Molecules. Vol.26, No.22 (2021)
Suggested Citation
Abdollah Ardebili, Mohammad Hassan Pouriayevali, Sahar Aleshikh, Marziyeh Zahani, Mehdi Ajorloo, Ahdieh Izanloo, Abolghasem Siyadatpanah, Hadi Razavi Nikoo, Polrat Wilairatana, Henrique Douglas Melo Coutinho Antiviral therapeutic potential of curcumin: An update. Molecules. Vol.26, No.22 (2021). doi:10.3390/molecules26226994 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/75964
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Title
Antiviral therapeutic potential of curcumin: An update
Abstract
The treatment of viral disease has become a medical challenge because of the increasing incidence and prevalence of human viral pathogens, as well as the lack of viable treatment alternatives, including plant-derived strategies. This review attempts to investigate the trends of research on in vitro antiviral effects of curcumin against different classes of human viral pathogens worldwide. Various electronic databases, including PubMed, Scopus, Web of Science, and Google Scholar were searched for published English articles evaluating the anti-viral activity of curcumin. Data were then extracted and analyzed. The forty-three studies (published from 1993 to 2020) that were identified contain data for 24 different viruses. The 50% cytotoxic concentration (CC50), 50% effective/inhibitory concentration (EC50/IC50), and stimulation index (SI) parameters showed that curcumin had antiviral activity against viruses causing diseases in humans. Data presented in this review highlight the potential antiviral applications of curcumin and open new avenues for further experiments on the clinical applications of curcumin and its derivatives.