Publication:
Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment

Issued Date

1990-01-01

Resource Type

Article

ISSN

15376613
00221899

DOI

10.1093/infdis/161.3.577

Other identifier(s)

2-s2.0-0025220120

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Infectious Diseases. Vol.161, No.3 (1990), 577-580

Suggested Citation

Sornchai Looareesuwan, Poonkasem Charoenpan, May Ho, Nicholas J. White, Juntra Karbwang, Danai Bunnag, Tranakchit Harinasuta Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment. Journal of Infectious Diseases. Vol.161, No.3 (1990), 577-580. doi:10.1093/infdis/161.3.577 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16167

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Title

Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment

Author(s)

Sornchai Looareesuwan
 Poonkasem Charoenpan
 May Ho
 Nicholas J. White
 Juntra Karbwang
 Danai Bunnag
 Tranakchit Harinasuta

Other Contributor(s)

Mahidol University
 Nuffield Department of Clinical Medicine
 University of Calgary

Abstract

A 24-year-old man with severe Plasmodium falciparum malaria died after 77 h of treatment with full parenteral doses of quinine. His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of pharmacokinetic factors in determining the therapeutic response in severe P. falciparum malaria. © 1990, University of Chicago. All rights reserved.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/16167

Collections

Scopus 1969-1990