Publication: Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren
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Issued Date
2016-07-01
Resource Type
ISSN
00029637
Other identifier(s)
2-s2.0-84977608691
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Mahidol University
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SCOPUS
Bibliographic Citation
American Journal of Tropical Medicine and Hygiene. Vol.95, No.1 (2016), 77-82
Suggested Citation
Brechje De Gier, Tran Thuy Nga, Pattanee Winichagoon, Marjoleine A. Dijkhuizen, Nguyen Cong Khan, Margot Van De Bor, Maiza Campos Ponce, Katja Polman, Frank T. Wieringa Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren. American Journal of Tropical Medicine and Hygiene. Vol.95, No.1 (2016), 77-82. doi:10.4269/ajtmh.15-0533 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/40797
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Title
Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren
Abstract
© Copyright 2016 by The American Society of Tropical Medicine and Hygiene. Soil-transmitted helminth (STH) infections and micronutrient deficiencies are closely related and often coexist among low-income populations. We studied the association between infections with specific STH species and micronutrient status in rural Vietnamese schoolchildren. Children (N = 510) aged 6-9 years were recruited from two primary schools. STH infections were determined in stool samples. Hemoglobin, ferritin, retinol, and zinc were measured in blood samples, as well as C-reactive protein to control for inflammation. Iodine excretion was measured in urine. Associations of single and multiple infections with Ascaris lumbricoides, Trichuris trichiura, and hookworm with micronutrient status (hemoglobin, plasma ferritin, retinol, zinc, and urinary iodine) were estimated by multiple regression analysis. Ascaris infections showed a specific and intensity-dependent negative association with Vitamin A. Trichuris and hookworm infections were associated with lower hemoglobin concentration, but not with plasma ferritin. Trichurisinfected children had zinc deficiency less often than uninfected children. In conclusion, our study shows species-specific associations between STH infections and micronutrient status in children. The different life cycles of STH species might have specific effects on the absorption or loss of specific micronutrients. Tailor-made combinations of deworming and nutritional interventions may be needed to improve child health and nutrition.