Publication: Monte carlo cellular automata simulation of receptor trafficking in cell signal transduction: Tracking dimer and oligomer formation
| dc.contributor.author | Chontita Rattanakul | en_US |
| dc.contributor.author | Yongwimon Lenbury | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | South Carolina Commission on Higher Education | en_US |
| dc.date.accessioned | 2018-11-23T09:28:28Z | |
| dc.date.available | 2018-11-23T09:28:28Z | |
| dc.date.issued | 2015-11-15 | en_US |
| dc.description.abstract | © 2015, Kasetsart University. All rights reserved. A cellular automata (CA) model of the signal transduction pathway mediated by calcium sensing (CaS) receptors was constructed to investigate the effects of different fractions of healthy (functional) and defective receptors. Receptor trafficking was allowed to take place leading to dimerization and oligomerization which exerted a positive impact on the receptor binding affinity. Snapshots of receptor trafficking and distribution over the cell membrane simulated by the CA model were compared with the no-trafficking case. | en_US |
| dc.identifier.citation | Kasetsart Journal - Natural Science. Vol.49, No.6 (2015), 1036-1046 | en_US |
| dc.identifier.issn | 00755192 | en_US |
| dc.identifier.other | 2-s2.0-84988810653 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/123456789/35071 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84988810653&origin=inward | en_US |
| dc.subject | Agricultural and Biological Sciences | en_US |
| dc.title | Monte carlo cellular automata simulation of receptor trafficking in cell signal transduction: Tracking dimer and oligomer formation | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84988810653&origin=inward | en_US |