Publication: Distribution of pathogenic Naegleria spp in Thailand
Issued Date
2001-12-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0035553358
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.32, No.SUPPL. 2 (2001), 172-178
Suggested Citation
Supathra Tiewcharoen, Virach Junnu Distribution of pathogenic Naegleria spp in Thailand. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.32, No.SUPPL. 2 (2001), 172-178. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/26635
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Title
Distribution of pathogenic Naegleria spp in Thailand
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Abstract
Research concerning the distribution, isolation, viability, ultrastructure, morphology and immunogenicity of Naegleria fowleri has been increasing in Thailand during 1988-2000. The distribution of the organism was carried out from 1985 to 1987 in Si Sa Ket and Ubon Rachathani Provinces, after the first fatal case was reported in Si Sa Ket. Since then in a 1998 survey of N. fowleri in stagnant water around industrial areas was carried out in Pathum Thani, Samut Prakan and Lopburi provinces. The results showed that 10% of pathogenic Naegleria belonged to species fowleri as characterized by morphology and the occurrence of pathogenesis in mice after nasal inoculation. In the same year, Nacapunchai et al (1999) determined the prevalence of amebae in aquatic habitat of human environments in five parts of Thailand during the summer. Fourteen percent of free living Naegleria spp were found in both soil and water resources. Recent studies of the ultrastructure, factors affecting the viability and SDS-PAGE electrophoretic patterns of 3 Thai strains of pathogenic Naegleria spp indicated their similarities in morphological characteristics of pathogenic reference control, Naegleria fowleri CDC VO 3081. Additional study using a genetic approach to species criteria using allozyme electrophoresis had been conducted.