Publication: The role of the environment in shaping the trends of childhood asthma – An Asian perspective
Issued Date
2021-08-01
Resource Type
ISSN
13993038
09056157
09056157
Other identifier(s)
2-s2.0-85104495359
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Mahidol University
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SCOPUS
Bibliographic Citation
Pediatric Allergy and Immunology. Vol.32, No.6 (2021), 1152-1164
Suggested Citation
Agnes S.Y. Leung, Elizabeth Huiwen Tham, Jing Li, Punchama Pacharn, Takumi Takizawa, Eun Lee, Yuhan Xing, Ting Fan Leung, Soo Jong Hong, Gary W.K. Wong The role of the environment in shaping the trends of childhood asthma – An Asian perspective. Pediatric Allergy and Immunology. Vol.32, No.6 (2021), 1152-1164. doi:10.1111/pai.13508 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/77252
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Title
The role of the environment in shaping the trends of childhood asthma – An Asian perspective
Abstract
Asthma has now become one of the most common atopic disorders not only in developed countries but also in many developing countries. The etiology is likely due to a complex interaction between genetic and environmental factors. In many Asian countries, the prevalence of asthma has also been documented by validated instruments to be increasing rapidly over the past two decades. However, studies in rural areas in Asia with a traditional farming environment revealed markedly lower asthma prevalence when compared with residents in nearby cities despite having similar genetic background. Among the environmental factors implicated in the pathogenesis of asthma, air pollution, dietary patterns, viral infections, and early microbial exposure have been studied extensively around the world. Asia provides many opportunities to study these potential factors as there are many ethnic groups living in distinctly different environments. The understanding of the roles of these factors in affecting the early immune system and subsequent development of asthma will enable us to develop potential primary preventive strategies against a disease which affects millions worldwide.