Publication: Cultivation of Plasmodium vivax
Issued Date
2008-02-01
Resource Type
ISSN
14714922
Other identifier(s)
2-s2.0-38349090489
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Mahidol University
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SCOPUS
Bibliographic Citation
Trends in Parasitology. Vol.24, No.2 (2008), 85-88
Suggested Citation
Rachanee Udomsangpetch, Osamu Kaneko, Kesinee Chotivanich, Jetsumon Sattabongkot Cultivation of Plasmodium vivax. Trends in Parasitology. Vol.24, No.2 (2008), 85-88. doi:10.1016/j.pt.2007.09.010 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/19376
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Title
Cultivation of Plasmodium vivax
Abstract
Establishment of a continuous line of Plasmodium vivax parasite is crucial to understand the parasite's biology; however, this has not yet been achieved. Beginning in the 19th century, there were several efforts to cultivate this malaria parasite but without much success until the late 1980s. In addition, to date, only minor modifications of the methodology have been investigated, which has resulted in extending the cultivation period to around four weeks by supplying reticulocytes obtained from normal blood or rare hemochromatotic blood. However, the use of laboratory-produced erythroblasts to cultivate P. vivax enables maintenance of a continuous line of the parasite stably in the laboratory. Here, we summarize and compare the available methodologies and conditions for the in vitro cultivation of P. vivax. © 2007 Elsevier Ltd. All rights reserved.