Publication: Recent advances of capillary electrophoresis in pharmaceutical analysis
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Issued Date
2010-09-01
Resource Type
ISSN
16182650
16182642
16182642
Other identifier(s)
2-s2.0-77955970593
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Mahidol University
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SCOPUS
Bibliographic Citation
Analytical and Bioanalytical Chemistry. Vol.398, No.1 (2010), 29-52
Suggested Citation
Leena Suntornsuk Recent advances of capillary electrophoresis in pharmaceutical analysis. Analytical and Bioanalytical Chemistry. Vol.398, No.1 (2010), 29-52. doi:10.1007/s00216-010-3741-5 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/28639
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Title
Recent advances of capillary electrophoresis in pharmaceutical analysis
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Abstract
This review covers recent advances of capillary electrophoresis (CE) in pharmaceutical analysis. The principle, instrumentation, and conventional modes of CE are briefly discussed. Advances in the different CE techniques (non-aqueous CE, microemulsion electrokinetic chromatography, capillary isotachophoresis, capillary electrochromatography, and immunoaffinity CE), detection techniques (mass spectrometry, light-emitting diode, fluorescence, chemiluminescence, and contactless conductivity), on-line sample pretreatment (flow injection) and chiral separation are described. Applications of CE to assay of active pharmaceutical ingredients (APIs), drug impurity testing, chiral drug separation, and determination of APIs in biological fluids published from 2008 to 2009 are tabulated. © 2010 Springer-Verlag.