Publication: Evolution of some variable-number tandem repeat loci among a group of Beijing strains of Mycobacterium tuberculosis
Issued Date
2007-11-01
Resource Type
ISSN
14729792
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2-s2.0-35348841489
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Mahidol University
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SCOPUS
Bibliographic Citation
Tuberculosis. Vol.87, No.6 (2007), 498-501
Suggested Citation
Pamaree Billamas, Nat Smittipat, Tada Juthayothin, Arunee Thong-On, Norio Yamada, Hideki Yanai, Prasit Palittapongarnpim Evolution of some variable-number tandem repeat loci among a group of Beijing strains of Mycobacterium tuberculosis. Tuberculosis. Vol.87, No.6 (2007), 498-501. doi:10.1016/j.tube.2007.08.005 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/24501
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Title
Evolution of some variable-number tandem repeat loci among a group of Beijing strains of Mycobacterium tuberculosis
Abstract
The patterns of variable-number tandem repeats (VNTR) genotypes of a clonal group of Mycobacterium tuberculosis Beijing isolates with very similar IS6110-restriction fragment length polymorphism (RFLP) patterns were studied. Differences between VNTR were mostly by a single repeat unit. However, a multiple-unit change also occurred. This suggests that a mechanism other than the slipped-strand mispairing might be responsible for the instability of VNTR in M. tuberculosis as well. This finding is useful for inferring phylogenetics of M. tuberculosis based on the VNTR genotypes. © 2007 Elsevier Ltd. All rights reserved.