Publication: Red cell and plasma calcium, copper and zinc in beta-thalassemia/hemoglobin E.
Issued Date
1991-06-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0026178420
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
The Southeast Asian journal of tropical medicine and public health. Vol.22, No.2 (1991), 171-175
Suggested Citation
K. U. Suthipark, A. Likidlilid, S. Fucharoen, P. Pootrakul, D. Shumnumsirivath, S. Ong-ajyooth, D. Plaskett, J. Webb Red cell and plasma calcium, copper and zinc in beta-thalassemia/hemoglobin E.. The Southeast Asian journal of tropical medicine and public health. Vol.22, No.2 (1991), 171-175. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/22138
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Title
Red cell and plasma calcium, copper and zinc in beta-thalassemia/hemoglobin E.
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Abstract
Beta-thalassemia/Hb E is a genetic disease prevalent in Thailand. This study has used atomic absorption spectroscopy to evaluate red cell and plasma calcium, copper and zinc in patients with beta-thalassemia/Hb E, both splenectomized and non-splenectomized. The levels of these trace elements in both red cells and plasma were different between the non-thalassemic controls and the disease patients. The most prominent result was that calcium concentration in red cells increased significantly in thalassemia subjects, particularly in splenectomized cases. These results might reflect the abnormal trace element metabolism and defects in the calcium transport system of the red cell membrane in thalassemia.