Publication: Closure of the patent foramen ovale in patients with embolic stroke of undetermined source: A clinical expert opinion and consensus statement for the Asian-Pacific region
Issued Date
2020-01-01
Resource Type
ISSN
17474949
17474930
17474930
Other identifier(s)
2-s2.0-85088090011
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal of Stroke. (2020)
Suggested Citation
Hans Christoph Diener, Teiji Akagi, Kritvikrom Durongpisitkul, Viji Samuel Thomson, A. T. Prabhakar, Ross Sharpe, Bert Albers, Thorsten Lewalter, Koichi Oki, Vijay K. Sharma Closure of the patent foramen ovale in patients with embolic stroke of undetermined source: A clinical expert opinion and consensus statement for the Asian-Pacific region. International Journal of Stroke. (2020). doi:10.1177/1747493020941658 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/58351
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Title
Closure of the patent foramen ovale in patients with embolic stroke of undetermined source: A clinical expert opinion and consensus statement for the Asian-Pacific region
Other Contributor(s)
National University Hospital, Singapore
Yong Loo Lin School of Medicine
Okayama University
Universität Duisburg-Essen
Faculty of Medicine, Siriraj Hospital, Mahidol University
Saiseikai Central Hospital
Christian Medical College, Vellore
Albers Clinical Evidence Consultancy
Peter Osypka Heart Center
Cardiology Department
Yong Loo Lin School of Medicine
Okayama University
Universität Duisburg-Essen
Faculty of Medicine, Siriraj Hospital, Mahidol University
Saiseikai Central Hospital
Christian Medical College, Vellore
Albers Clinical Evidence Consultancy
Peter Osypka Heart Center
Cardiology Department
Abstract
© 2020 World Stroke Organization. Recently published long-term data from randomized controlled trials have provided evidence for the prevention of recurrent embolic stroke of undetermined source by percutaneous closure of the patent foramen ovale. However, most data were obtained from Caucasian populations and evidence on patent foramen ovale closure in Asian-Pacific patients is limited. The relative paucity in clinical data from this population, as well as the fact that Asian-Pacific patients may have higher bleeding risks than Caucasians, complicates clinical decision-making. This document, resulting from a consensus meeting of Asian-Pacific clinical experts, states the consensus among these experts about how to treat Asian-Pacific patients who had an embolic stroke of undetermined source and have a patent foramen ovale, based on currently available evidence and expert opinions. In addition, uncertainties and the need for clinical data regarding patent foramen ovale closure for prevention of recurrent embolic stroke of undetermined source in general, and specifically for Asian-Pacific patients, are identified.