Publication:
Call to Action: SARS-CoV-2 and CerebrovAscular DisordErs (CASCADE)

Issued Date

2020-09-01

Resource Type

Article

ISSN

15328511
10523057

DOI

10.1016/j.jstrokecerebrovasdis.2020.104938

Other identifier(s)

2-s2.0-85086253184

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Stroke and Cerebrovascular Diseases. Vol.29, No.9 (2020)

Suggested Citation

Shahram Abootalebi, Benjamin M. Aertker, Mohammad Sobhan Andalibi, Negar Asdaghi, Ozlem Aykac, M. Reza Azarpazhooh, M. Cecilia Bahit, Kristian Barlinn, Hamidon Basri, Reza Bavarsad Shahripour, Anna Bersano, Jose Biller, Afshin Borhani-Haghighi, Robert D. Brown, Bruce CV Campbell, Salvador Cruz-Flores, Deidre Anne De Silva, Mario Di Napoli, Afshin A. Divani, Randall C. Edgell, Johanna T. Fifi, Abdoreza Ghoreishi, Teruyuki Hirano, Keun Sik Hong, Chung Y. Hsu, Josephine F. Huang, Manabu Inoue, Amanda L. Jagolino, Moira Kapral, Hoo Fan Kee, Zafer Keser, Rakesh Khatri, Masatoshi Koga, Jerzy Krupinski, David S. Liebeskind, Liping Liu, Henry Ma, Alberto Maud, Louise D. McCullough, Dawn Matherne Meyer, Victoria Mifsud, Negar Morovatdar, Yongchai Nilanont, Thomas J. Oxley, Atilla Özcan Özdemir, Jeyaraj Pandian, Leonardo Pantoni, Nikolaos I.H. Papamitsakis, Adrian Parry-Jones, Thanh Phan, Gustavo Rodriguez, Jose G. Romano, Ziad Sabaa-Ayoun, Hamidreza Saber, Payam Sasannezhad, Jeffrey L. Saver, Eugene Scharf, Ashfaq Shuaib, Brian Silver, Shaloo Singhal, Craig J. Smith, Saverio Stranges, P. N. Sylaja, Michel Torbey, Kazunori Toyoda, Georgios Tsivgoulis, Mohammad Wasay, Nawaf Yassi, Takeshi Yoshimoto, Babak Zamani, Ramin Zand Call to Action: SARS-CoV-2 and CerebrovAscular DisordErs (CASCADE). Journal of Stroke and Cerebrovascular Diseases. Vol.29, No.9 (2020). doi:10.1016/j.jstrokecerebrovasdis.2020.104938 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/58028

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Call to Action: SARS-CoV-2 and CerebrovAscular DisordErs (CASCADE)

Author(s)

Shahram Abootalebi
 Benjamin M. Aertker
 Mohammad Sobhan Andalibi
 Negar Asdaghi
 Ozlem Aykac
 M. Reza Azarpazhooh
 M. Cecilia Bahit
 Kristian Barlinn
 Hamidon Basri
 Reza Bavarsad Shahripour
 Anna Bersano
 Jose Biller
 Afshin Borhani-Haghighi
 Robert D. Brown
 Bruce CV Campbell
 Salvador Cruz-Flores
 Deidre Anne De Silva
 Mario Di Napoli
 Afshin A. Divani
 Randall C. Edgell
 Johanna T. Fifi
 Abdoreza Ghoreishi
 Teruyuki Hirano
 Keun Sik Hong
 Chung Y. Hsu
 Josephine F. Huang
 Manabu Inoue
 Amanda L. Jagolino
 Moira Kapral
 Hoo Fan Kee
 Zafer Keser
 Rakesh Khatri
 Masatoshi Koga
 Jerzy Krupinski
 David S. Liebeskind
 Liping Liu
 Henry Ma
 Alberto Maud
 Louise D. McCullough
 Dawn Matherne Meyer
 Victoria Mifsud
 Negar Morovatdar
 Yongchai Nilanont
 Thomas J. Oxley
 Atilla Özcan Özdemir
 Jeyaraj Pandian
 Leonardo Pantoni
 Nikolaos I.H. Papamitsakis
 Adrian Parry-Jones
 Thanh Phan
 Gustavo Rodriguez
 Jose G. Romano
 Ziad Sabaa-Ayoun
 Hamidreza Saber
 Payam Sasannezhad
 Jeffrey L. Saver
 Eugene Scharf
 Ashfaq Shuaib
 Brian Silver
 Shaloo Singhal
 Craig J. Smith
 Saverio Stranges
 P. N. Sylaja
 Michel Torbey
 Kazunori Toyoda
 Georgios Tsivgoulis
 Mohammad Wasay
 Nawaf Yassi
 Takeshi Yoshimoto
 Babak Zamani
 Ramin Zand

Other Contributor(s)

Clinical Neurology Research Center
 Beijing Tiantan Hospital, Capital Medical University
 Luxembourg Institute of Health
 The Aga Khan University
 UNM School of Medicine
 University of Alberta
 University of California, San Diego
 Robarts Research Institute
 University of Miami
 Eskişehir Osmangazi Üniversitesi
 St. Louis University
 Sree Chitra Tirunal Institute for Medical Sciences and Technology
 University of Melbourne
 Dresden University Faculty of Medicine and University Hospital Carl Gustav Carus
 Universiti Putra Malaysia
 Iran University of Medical Sciences
 SUNY Downstate Health Sciences University
 Manchester Metropolitan University
 Cleveland Clinic Foundation
 Kyorin University
 Monash University
 Singapore General Hospital
 Institute for Clinical Evaluative Sciences
 Foundation IRCCS Neurological Institute "C. Besta"
 University of Toronto
 Loyola University Health System
 Kokuritsu Junkankibyo Senta
 Dalhousie University
 Attikon University Hospital
 Inje University
 Icahn School of Medicine at Mount Sinai
 University of Zanjan
 Faculty of Medicine, Siriraj Hospital, Mahidol University
 Western University
 Salford Royal NHS FoundationTrust
 Geisinger Health System
 China Medical University Taichung
 Christian Medical College & Hospital, Ludhiana
 Mayo Clinic
 David Geffen School of Medicine at UCLA
 The Mount Sinai Hospital
 The University of Manchester
 Mayo Clinic in Jacksonville, Florida
 Ospedale Luigi Sacco - Polo Universitario
 University of Tennessee Health Science Center
 Mashhad University of Medical Sciences
 University of Massachusetts Medical School
 Chief of Cardiology
 UTHealth McGovern Medical School
 SMDN-Centre for Cardiovascular Medicine and Cerebrovascular Disease Prevention
 Texas Tech Health University Health Sciences Center
 Hospital Universitari Mútua Terrassa
 San Camillo de' Lellis District General Hospital

Abstract

© 2020 Background and purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), now named coronavirus disease 2019 (COVID-19), may change the risk of stroke through an enhanced systemic inflammatory response, hypercoagulable state, and endothelial damage in the cerebrovascular system. Moreover, due to the current pandemic, some countries have prioritized health resources towards COVID-19 management, making it more challenging to appropriately care for other potentially disabling and fatal diseases such as stroke. The aim of this study is to identify and describe changes in stroke epidemiological trends before, during, and after the COVID-19 pandemic. Methods: This is an international, multicenter, hospital-based study on stroke incidence and outcomes during the COVID-19 pandemic. We will describe patterns in stroke management, stroke hospitalization rate, and stroke severity, subtype (ischemic/hemorrhagic), and outcomes (including in-hospital mortality) in 2020 during COVID-19 pandemic, comparing them with the corresponding data from 2018 and 2019, and subsequently 2021. We will also use an interrupted time series (ITS) analysis to assess the change in stroke hospitalization rates before, during, and after COVID-19, in each participating center. Conclusion: The proposed study will potentially enable us to better understand the changes in stroke care protocols, differential hospitalization rate, and severity of stroke, as it pertains to the COVID-19 pandemic. Ultimately, this will help guide clinical-based policies surrounding COVID-19 and other similar global pandemics to ensure that management of cerebrovascular comorbidity is appropriately prioritized during the global crisis. It will also guide public health guidelines for at-risk populations to reduce risks of complications from such comorbidities.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/58028

Collections

Scopus 2020