Publication:
Plasma prefractionation methods for proteomic analysis and perspectives in clinical applications

2

Issued Date

2017-07-01

Resource Type

Review

ISSN

18628354
18628346

DOI

10.1002/prca.201600135

Other identifier(s)

2-s2.0-85017227344

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Proteomics - Clinical Applications. Vol.11, No.7-8 (2017)

Suggested Citation

Somchai Chutipongtanate, Supawat Chatchen, Jisnuson Svasti Plasma prefractionation methods for proteomic analysis and perspectives in clinical applications. Proteomics - Clinical Applications. Vol.11, No.7-8 (2017). doi:10.1002/prca.201600135 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/41852

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Title

Plasma prefractionation methods for proteomic analysis and perspectives in clinical applications

Author(s)

Somchai Chutipongtanate
 Supawat Chatchen
 Jisnuson Svasti

Other Contributor(s)

Mahidol University
 Chulabhorn Research Institute
 Chulabhorn Graduate Institute

Abstract

© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Plasma is a rich source of biomarkers with clinical relevance. However, the wide dynamic range of protein concentration hinders the detection of low abundance proteins. Plasma prefractionation methods serve as indispensable tools to reduce plasma complexity, allowing the opportunity to explore tissue-derived proteins which leak into the circulation. This review summarizes common approaches in plasma prefractionation methods for proteomic analysis and then discusses some considerations in plasma prefractionation for clinical applications, reviewing some examples of its use in clinical situations.

Keyword(s)

Biochemistry, Genetics and Molecular Biology

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/41852

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Scopus 2016-2017
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