Publication: Does Microinvasive Adenocarcinoma of Cervix Have Poorer Treatment Outcomes than Microinvasive Squamous Cell Carcinoma?
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Issued Date
2016-01-01
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2476762X
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2-s2.0-85015355863
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Mahidol University
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SCOPUS
Bibliographic Citation
Asian Pacific journal of cancer prevention : APJCP. Vol.17, No.8 (2016), 4013-4017
Suggested Citation
Irene Ruengkhachorn, Suchanan Hanamornroongruang, Chairat Leelaphatanadit, Suthi Sangkarat Does Microinvasive Adenocarcinoma of Cervix Have Poorer Treatment Outcomes than Microinvasive Squamous Cell Carcinoma?. Asian Pacific journal of cancer prevention : APJCP. Vol.17, No.8 (2016), 4013-4017. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/43136
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Title
Does Microinvasive Adenocarcinoma of Cervix Have Poorer Treatment Outcomes than Microinvasive Squamous Cell Carcinoma?
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Abstract
BACKGROUND: To compare the pathological findings and oncologic outcomes of stage IA cervical carcinoma patients, between adenocarcinoma and squamous cell carcinoma cases.MATERIALS AND METHODS: A total of 151 medical records of stage IA cervical carcinoma patients undergoing primary surgical treatment during 2006-2013 were reviewed. Information from pathological diagnosis and recurrence rates were compared with descriptive statistical analysis. The Kaplan-Meier method and Cox proportional hazards model were used for survival analysis.RESULTS: The median age was 48.9 years. There was no significant difference in rates of lymph node, parametrium, uterine, vaginal, or ovarian metastasis, when comparing adenocarcinoma with squamous cell carcinoma. Overall recurrence rates of adenocarcinoma (5.7%) and squamous cell carcinoma (2.6%) were not statistically significant different, even when stratified by stage. When comparing progression free survival with squamous cell carcinoma, adenocarcinoma had an HR of 0.448 (0.073-2.746), p=0.386.CONCLUSIONS: Microinvasive adenocarcinoma of cervix has similar rate of extracervical involvement and oncologic outcomes to squamous cell carcinoma.