Publication: Inpatient burden and mortality of heatstroke in the United States
2
Issued Date
2021-04-01
Resource Type
ISSN
17421241
13685031
13685031
Other identifier(s)
2-s2.0-85096861876
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Clinical Practice. Vol.75, No.4 (2021)
Suggested Citation
Wisit Kaewput, Charat Thongprayoon, Tananchai Petnak, Liam D. Cato, Api Chewcharat, Boonphiphop Boonpheng, Tarun Bathini, Saraschandra Vallabhajosyula, Wisit Cheungpasitporn Inpatient burden and mortality of heatstroke in the United States. International Journal of Clinical Practice. Vol.75, No.4 (2021). doi:10.1111/ijcp.13837 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/78339
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Inpatient burden and mortality of heatstroke in the United States
Abstract
Background: This study aimed to assess inpatient prevalence, characteristics, outcomes, and resource utilisation of hospitalisation for heatstroke in the United States. Additionally, this study aimed to explore factors associated with in-hospital mortalities of heatstroke. Methods: The 2003-2014 National Inpatient Sample database was used to identify hospitalised patients with a principal diagnosis of heatstroke. The inpatient prevalence, clinical characteristics, in-hospital treatments, outcomes, length of hospital stay, and hospitalisation cost were studied. Multivariable logistic regression was performed to identify independent factors associated with in-hospital mortality. Results: A total of 3372 patients were primarily admitted for heatstroke, accounting for an overall inpatient prevalence of heatstroke amongst hospitalised patients of 36.3 cases per 1 000 000 admissions in the United States with an increasing trend during the study period (P <.001). Age 40-59 was the most prevalent age group. During the hospital stay, 20% required mechanical ventilation, and 2% received renal replacement therapy. Rhabdomyolysis was the most common complication. Renal failure was the most common end-organ failure, followed by neurological, respiratory, metabolic, hematologic, circulatory, and liver systems. The in-hospital mortality rate of heatstroke hospitalisation was 5% with a decreasing trend during the study period (P <.001). The presence of end-organ failure was associated with increased in-hospital mortality, whereas more recent years of hospitalisation was associated with decreased in-hospital mortality. The median length of hospital stay was 2 days. The median hospitalisation cost was $17 372. Conclusion: The inpatient prevalence of heatstroke in the United States increased, while the in-hospital mortality of heatstroke decreased.