Southeast Asian Journal of Tropical Medicine and Public Health. Vol.11, No.3 (1980), 408-412
Suggested Citation
Y. Chomcharn, K. Surathin, D. Bunnag, S. Sucharit, T. Harinasuta Effect of a single dose of primaquine on a Thai strain of Plasmodium falciparum. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.11, No.3 (1980), 408-412. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/11118
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Effect of a single dose of primaquine on a Thai strain of Plasmodium falciparum
A single dose of 45 mg of primaquine base was effective in the elimination of gametocytes of the possibly chloroquine-resistant P. falciparum in Thailand. The gametocyte counts decreased markedly within 3.5 days, showing a significant difference from the control in which gametocytes mostly still remain within 11.4 days. The development of the gametocytes in A. dirus was not observed after treatment. Primaquine can be used as a gametocytocide and sporontocide for falciparum malaria in Thailand if the drug is administered when matured gametocytes appear in the peripheral blood.
