Publication: Medical progress: Melioidosis
Issued Date
2012-09-13
Resource Type
ISSN
15334406
00284793
00284793
Other identifier(s)
2-s2.0-84866067768
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
New England Journal of Medicine. Vol.367, No.11 (2012), 1035-1044
Suggested Citation
W. Joost Wiersinga, Bart J. Currie, Sharon J. Peacock Medical progress: Melioidosis. New England Journal of Medicine. Vol.367, No.11 (2012), 1035-1044. doi:10.1056/NEJMra1204699 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/14623
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Title
Medical progress: Melioidosis
Abstract
MELIOIDOSIS, CAUSED BY THE ENVIRONMENTAL GRAM-NEGATIVE BACILlus Burkholderia pseudomallei, is classically characterized by pneumonia and multiple abscesses, with a mortality rate of up to 40%. It is an important cause of community-acquired sepsis in Southeast Asia and northern Australia. Its known global distribution is expanding, a reflection of improvements in diagnostic microbiology and increasing numbers of cases in travelers and returning military personnel (Fig. 1). 1,2 A locally acquired case of melioidosis was recently described in the United States. 3 B. pseudomallei has been classified by the Centers for Disease Control and Prevention as a category B bioterrorism agent, resulting in increased research and understanding of melioidosis. This review considers recent developments in pathogenesis, diagnostics, and treatment. Copyright © 2012 Massachusetts Medical Society.