Perioperative Complications and Mortality Following Radical Cystectomy and Urinary Diversion in Bladder Cancer in Ramathibodi Hospital

Abstract

Objective: To review the complications of mortality rate after radical cystectomy in Ramathibodi Hospital and analysis for the possible contributing factors to the outcome after the procedure. Methods: All patients who underwent radical cystectomy with urinary diversion between January 2005 to December 2011 were retrospectively reviewed. Preoperative patient characteristics and preoperative data were recorded. Perioperative morbidity and mortality within 90 days after surgery were analyzed for the possible contributing factors with univariate and multivariate analysis. Results: Of all 106 patients, 90 men and 16 women, with mean age of 65.6 year (33 - 88 years). Postoperative complications within 90 days were observed in 38 (35.5%) of the patients, the most common complication being sepsis 17 (16.0%) cases, followed by wound infection/dehiscence 12 (11.3%) cases and urine leak/collection 6 (5.6%) cases. The 90-d mortality rate was 8.4%. Age was the only factor that significantly affected perioperative and mortality. Conclusions: Although age more than 70 years significantly affected perioperative morbidity and mortality, properly selected elderly patients who were reasonably in good health were found to be safe for radical cystectomy with urinary diversion for treatment of invasive bladder carcinoma patients.