Publication:
Isolation and structure elucidation of enniatins L, M<inf>1</inf>, M<inf>2</inf>, and N: Novel hydroxy analogs

Issued Date

2004-10-04

Resource Type

Article

ISSN

0018019X

DOI

10.1002/hlca.200490185

Other identifier(s)

2-s2.0-4644288194

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Helvetica Chimica Acta. Vol.87, No.8 (2004), 2066-2073

Suggested Citation

Pornrapee Vongvilai, Masahiko Isaka, Prasat Kittakoop, Prasert Srikitikulchai, Palangpon Kongsaeree, Samran Prabpai, Yodhathai Thebtaranonth Isolation and structure elucidation of enniatins L, M<inf>1</inf>, M<inf>2</inf>, and N: Novel hydroxy analogs. Helvetica Chimica Acta. Vol.87, No.8 (2004), 2066-2073. doi:10.1002/hlca.200490185 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/21144

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Title

Isolation and structure elucidation of enniatins L, M<inf>1</inf>, M<inf>2</inf>, and N: Novel hydroxy analogs

Author(s)

Pornrapee Vongvilai
 Masahiko Isaka
 Prasat Kittakoop
 Prasert Srikitikulchai
 Palangpon Kongsaeree
 Samran Prabpai
 Yodhathai Thebtaranonth

Other Contributor(s)

Mahidol University
 Thailand National Center for Genetic Engineering and Biotechnology

Abstract

Four new cyclohexadepsipeptides, enniatins L (1), M1(2), M2(3), and N (4), have been isolated from an unidentified fungus (BCC 2629), together with the known enniatins B (5), H (6), and I (7), MK1688 (8), and enniatin B4(9). Compounds 1-4 are the first enniatin analogs with an OH group at the side chain of one of the 2-hydroxycarboxylic acid residues. The structures of 1-4 were elucidated by spectroscopic means and by X-ray crystallography.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemical Engineering
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/21144

Collections

Scopus 2001-2005