Publication:
Antimalarial sesquiterpenes from tubers of Cyperus rotundus: structure of 10,12-Peroxycalamenene, a sesquiterpene endoperoxide

Issued Date

1995-01-01

Resource Type

Article

ISSN

00319422

DOI

10.1016/0031-9422(95)00260-E

Other identifier(s)

2-s2.0-0029360451

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Phytochemistry. Vol.40, No.1 (1995), 125-128

Suggested Citation

C. Thebtaranonth, Y. Thebtaranonth, S. Wanauppathamkul, Y. Yuthavong Antimalarial sesquiterpenes from tubers of Cyperus rotundus: structure of 10,12-Peroxycalamenene, a sesquiterpene endoperoxide. Phytochemistry. Vol.40, No.1 (1995), 125-128. doi:10.1016/0031-9422(95)00260-E Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/17232

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Title

Antimalarial sesquiterpenes from tubers of Cyperus rotundus: structure of 10,12-Peroxycalamenene, a sesquiterpene endoperoxide

Author(s)

C. Thebtaranonth
 Y. Thebtaranonth
 S. Wanauppathamkul
 Y. Yuthavong

Other Contributor(s)

Thailand National Science and Technology Development Agency
 Mahidol University
 Thailand National Center for Genetic Engineering and Biotechnology

Abstract

Activity-guided investigation of Cyperus rotundus tubers led to the isolation of patchoulenone, caryophyllene α-oxide, 10,12-peroxycalamenene and 4,7-dimethyl-1-tetralone. The antimalarial activities of these compounds are in the range of EC5010-4-10-6M, with the novel endoperoxide sesquiterpene, 10,12-peroxycalamenene, exhibiting the strongest effect at EC502.33 × 10-6M. © 1995.

Keyword(s)

Agricultural and Biological Sciences
 Biochemistry, Genetics and Molecular Biology
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/17232

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Scopus 1991-2000