Publication: Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp.
Issued Date
2000-01-01
Resource Type
ISSN
01252208
Other identifier(s)
2-s2.0-0034099761
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.83, No.1 (2000), 57-60
Suggested Citation
Somboon Srimuang, Angkana Chaiprasert, Deja Tanphaichitra, Chularut Prariyachatigul, Watcharin Rungsipanuratn Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp.. Journal of the Medical Association of Thailand. Vol.83, No.1 (2000), 57-60. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/26344
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Title
Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp.
Abstract
Seventy-one isolates of Cryptococcus neoformans and 5 isolates of Prototheca spp. were tested for in vitro susceptibility against amphotericin B alone and against the combination of amphotericin B with each clinically relevant concentration of flucytosine (5-FC) and rifampin by broth dilution methods. The combinations of amphotericin B and rifampin produced greater effect on reduction of the minimal inhibition concentration (MIC) of amphotericin B than did either drug used individually. Flucytosine combined with amphotericin B produced little or no reduction of the MIC compared with amphotericin B alone.