Publication:
Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of triterpenoids isolated from leaves and twigs of Gardenia carinata

Issued Date

2013-04-26

Resource Type

Article

ISSN

15206025
01633864

DOI

10.1021/np3006887

Other identifier(s)

2-s2.0-84876903120

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Natural Products. Vol.76, No.4 (2013), 530-537

Suggested Citation

Naowarat Kongkum, Patoomratana Tuchinda, Manat Pohmakotr, Vichai Reutrakul, Pawinee Piyachaturawat, Surawat Jariyawat, Kanoknetr Suksen, Radeekorn Akkarawongsapat, Jitra Kasisit, Chanita Napaswad Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of triterpenoids isolated from leaves and twigs of Gardenia carinata. Journal of Natural Products. Vol.76, No.4 (2013), 530-537. doi:10.1021/np3006887 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/31325

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Title

Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of triterpenoids isolated from leaves and twigs of Gardenia carinata

Author(s)

Naowarat Kongkum
 Patoomratana Tuchinda
 Manat Pohmakotr
 Vichai Reutrakul
 Pawinee Piyachaturawat
 Surawat Jariyawat
 Kanoknetr Suksen
 Radeekorn Akkarawongsapat
 Jitra Kasisit
 Chanita Napaswad

Other Contributor(s)

Mahidol University

Abstract

Eight new cycloartane triterpenoids (1-8), named carinatins A-H, and the known compounds secaubryolide (9) and dikamaliartane D (10) were isolated from the leaves and twigs of Gardenia carinata. Their structures were determined on the basis of spectroscopic methods. Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of compounds 1-7, 9, and 10 were investigated. © 2013 The American Chemical Society and American Society of Pharmacognosy.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Medicine
 Pharmacology, Toxicology and Pharmaceutics

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URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/31325

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