Publication:
Reduction of Ca2+ uptake induced by ionophore A23187 of red cells from malaria (Plasmodium berghei)-infected mice

Issued Date

1983-01-01

Resource Type

Article

ISSN

03091651

DOI

10.1016/0309-1651(83)90231-X

Other identifier(s)

2-s2.0-0020645817

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Cell Biology International Reports. Vol.7, No.3 (1983), 237-244

Suggested Citation

Jerapan Krungkrai, Yongyuth Yuthavong Reduction of Ca2+ uptake induced by ionophore A23187 of red cells from malaria (Plasmodium berghei)-infected mice. Cell Biology International Reports. Vol.7, No.3 (1983), 237-244. doi:10.1016/0309-1651(83)90231-X Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/30437

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Title

Reduction of Ca2+ uptake induced by ionophore A23187 of red cells from malaria (Plasmodium berghei)-infected mice

Author(s)

Jerapan Krungkrai
 Yongyuth Yuthavong

Other Contributor(s)

Mahidol University

Abstract

The Ca2+ionophore A23187 has much less capacity to induce Ca2+uptake of red cells from P. berghei-infected mice than of cells from normal mice. The reduction in Ca2+uptake occurs in both uninfacted and infected cells at all stages in the infected blood, as shown from experiments with cells separated on colloidal silica density gradient. Measurement of the ionophore concentration in the medium reveals that the ionophore is partitioned into red cells from infected blood to a greater extent than cells from normal blood. The reduction in A23187-induced Ca2+uptake may be due to difference in the interaction of red cell membrane with the ionophore, and its already high Ca2+permeability. © 1983.

Keyword(s)

Biochemistry, Genetics and Molecular Biology

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URI

https://repository.li.mahidol.ac.th/handle/123456789/30437

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Scopus 1969-1990