Publication:
A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future

Issued Date

2021-10-29

Resource Type

Review

ISSN

18732518
0264410X

DOI

10.1016/j.vaccine.2021.08.010

Other identifier(s)

2-s2.0-85117200775

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Vaccine. Vol.39, No.45 (2021), 6573-6584

Suggested Citation

Kristine A. Moore, Julia T. Ostrowsky, Alison M. Kraigsley, Angela J. Mehr, Joseph S. Bresee, Martin H. Friede, Bruce G. Gellin, Josephine P. Golding, Peter J. Hart, Ann Moen, Charlotte L. Weller, Michael T. Osterholm, William Ampofo, Wendy Barclay, Marco Cavaleri, Cheryl Cohen, Benjamin Cowling, Rebecca Cox, Ian Gust, Bruce Innis, Gagandeep Kang, Jacqueline Katz, Florian Krammer, Punnee Pitisuttithum, Diane Post, Larisa Rudenko, Marilda Siqueira, Jerry Weir A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future. Vaccine. Vol.39, No.45 (2021), 6573-6584. doi:10.1016/j.vaccine.2021.08.010 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/75994

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future

Author(s)

Kristine A. Moore
 Julia T. Ostrowsky
 Alison M. Kraigsley
 Angela J. Mehr
 Joseph S. Bresee
 Martin H. Friede
 Bruce G. Gellin
 Josephine P. Golding
 Peter J. Hart
 Ann Moen
 Charlotte L. Weller
 Michael T. Osterholm
 William Ampofo
 Wendy Barclay
 Marco Cavaleri
 Cheryl Cohen
 Benjamin Cowling
 Rebecca Cox
 Ian Gust
 Bruce Innis
 Gagandeep Kang
 Jacqueline Katz
 Florian Krammer
 Punnee Pitisuttithum
 Diane Post
 Larisa Rudenko
 Marilda Siqueira
 Jerry Weir

Other Contributor(s)

European Medicines Agency
 Institute of Experimental Medicine of the North-West Branch of the Russian Academy of Medical Sciences
 National Institute for Communicable Diseases
 Universitetet i Bergen
 University of Minnesota Twin Cities
 Organisation Mondiale de la Santé
 University of Melbourne
 Fundacao Oswaldo Cruz
 Wellcome Trust
 Centers for Disease Control and Prevention
 University of Ghana
 Imperial College London
 Icahn School of Medicine at Mount Sinai
 Mahidol University
 Food and Drug Administration
 National Institutes of Health (NIH)
 The University of Hong Kong
 Christian Medical College, Vellore
 PATH Center for Vaccine Innovation & Access
 The Sabin Vaccine Institute
 Center for Infectious Disease Research and Policy

Abstract

Improved influenza vaccines are urgently needed to reduce the burden of seasonal influenza and to ensure a rapid and effective public-health response to future influenza pandemics. The Influenza Vaccines Research and Development (R&D) Roadmap (IVR) was created, through an extensive international stakeholder engagement process, to promote influenza vaccine R&D. The roadmap covers a 10-year timeframe and is organized into six sections: virology; immunology; vaccinology for seasonal influenza vaccines; vaccinology for universal influenza vaccines; animal and human influenza virus infection models; and policy, finance, and regulation. Each section identifies barriers, gaps, strategic goals, milestones, and additional R&D priorities germane to that area. The roadmap includes 113 specific R&D milestones, 37 of which have been designated high priority by the IVR expert taskforce. This report summarizes the major issues and priority areas of research outlined in the IVR. By identifying the key issues and steps to address them, the roadmap not only encourages research aimed at new solutions, but also provides guidance on the use of innovative tools to drive breakthroughs in influenza vaccine R&D.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Immunology and Microbiology
 Medicine
 Veterinary

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/75994

Collections

Scopus 2021