Publication: Recent Advances of Hepatitis B Detection towards Paper-Based Analytical Devices
Issued Date
2021-01-01
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ISSN
1537744X
23566140
23566140
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2-s2.0-85102522373
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Mahidol University
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SCOPUS
Bibliographic Citation
Scientific World Journal. Vol.2021, (2021)
Suggested Citation
Aulia A. Tyas, Septi F. Raeni, Setyawan P. Sakti, Akhmad Sabarudin Recent Advances of Hepatitis B Detection towards Paper-Based Analytical Devices. Scientific World Journal. Vol.2021, (2021). doi:10.1155/2021/6643573 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/76400
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Title
Recent Advances of Hepatitis B Detection towards Paper-Based Analytical Devices
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Abstract
Hepatitis B virus (HBV) still remains a major global public health problem. One-half to one-third of the total HBV infected people died due to late detection of HBV. Serological antigen and viral HBV detections can help in the diagnosis, referral, and treatment of HBV. Available methods for HBV detection mostly used bulky instruments. Miniaturization of devices for HBV detection has been started by narrowing down the size of the devices. Several methods have also been proposed to increase the selectivity and sensitivity of the miniaturized methods, such as sandwich recognition of the biomarkers and the use of nano- to micro-sized materials. This review presents recent HBV detections in the last two decades from laboratory-based instruments towards microfluidic paper-based analytical devices (μPADs) for point-of-care testing (POCT) purposes. Early and routine analysis to detect HBV as early as possible could be achieved by POCT, especially for areas with limited access to a central laboratory and/or medical facilities.