Publication: Overweight and obesity as protective factors in severe falciparum Malaria
Issued Date
2019-05-01
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ISSN
01251562
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2-s2.0-85068918938
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.50, No.3 (2019), 421-427
Suggested Citation
Polrat Wilairatana, Noppadon Tangpukdee, Srivicha Krudsood, Nalinrat Wilairat, Pichayapat Wilairat, Pimjira Thebpatipat Overweight and obesity as protective factors in severe falciparum Malaria. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.50, No.3 (2019), 421-427. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/51688
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Title
Overweight and obesity as protective factors in severe falciparum Malaria
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Abstract
© 2019, SEAMEO TROPMED Network. All rights reserved. We conducted the study to determine if body mass index (BMI) could have any influence on severity of falciparum malaria. Severe (n = 196) (defined following World Health Organization criteria of 2015) and uncomplicated (n = 380) falciparum malaria patients were enrolled. Based on BMI criteria, the severe malaria group comprised 17% underweight, 70% normal weight, 9% overweight, and 4% obese patients, while in the uncomplicated malaria group the patients constituted 22%, 73%, 3%, and 2%, respectively. In both severe and uncomplicated malaria groups, significantly lower circulating parasite density and creatinine level were present in obese compared to patients in other BMI categories (p<0.05). Thus, obesity might be an indicator of reduced severity in falciparum malaria.