Publication: Rapid diagnosis of cytomegalovirus in Thai pediatric AIDS patients
Issued Date
2002-12-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0036595974
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.33, No.2 (2002), 306-311
Suggested Citation
Surang Tantivanich, Wandee Sawatmongkonkun, Kruavan Balachandra, Tawee Chotpitayasunondh, Pornsawan Amarapal Rapid diagnosis of cytomegalovirus in Thai pediatric AIDS patients. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.33, No.2 (2002), 306-311. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/20291
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Title
Rapid diagnosis of cytomegalovirus in Thai pediatric AIDS patients
Abstract
Blood samples were collected from 100 pediatric AIDS patients for the detection of CMV in pp65-bearing leukocytes (PBLs) by immunoperoxidase staining (IP) and PCR. IgM antibody assay was performed to determine the correlation of antigen and antibody. IP and PCR can be used as methods for the early detection of CMV (prior to the presence of IgM antibody). The sensitivity and specificity of IP were 73% and 97% respectively. IP is superior to PCR in several ways: it is very easy to perform, less time consuming, less expensive, and does not require expensive instruments.