Publication: Hypogonadism in thalassemia major patients
Issued Date
2016-09-01
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ISSN
22146237
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2-s2.0-84983565584
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Clinical and Translational Endocrinology. Vol.5, (2016), 42-45
Suggested Citation
Sasima Srisukh, Boonsong Ongphiphadhanakul, Pongamorn Bunnag Hypogonadism in thalassemia major patients. Journal of Clinical and Translational Endocrinology. Vol.5, (2016), 42-45. doi:10.1016/j.jcte.2016.08.001 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/42935
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Title
Hypogonadism in thalassemia major patients
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Abstract
© 2016 The Authors Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients. Hypogonadism, mostly hypogonadotropic hypogonadism, is usually detected during puberty. Early diagnosis and treatment are crucial for normal pubertal development and to reduce the complications of hypogonadism. The risks and benefits of hormonal replacement therapy, especially regarding the thromboembolic event, remain a challenge for providers caring for thalassemic patients.